Competitively sponging
Webcirc_0003266 promoted PDCD4 expression by competitively sponging miR-503-5p. Conclusion: Circ_0003266 suppresses the CRC progression via sponging miR-503-5p and regulating PDCD4 expressions, which suggests that circ_0003266 may serve as a novel target for the treatment of CRC. Keywords: Colorectal cancer, circ_0003266, miR-503 … WebAug 1, 2024 · In this study, we constructed a chemoresistance-related lncRNA-associated ceRNA network of CRC and confirmed the critical role of this regulatory network in 5-Fu and DDP resistance in CRC cells. We found that LINC02418 promoted CRC chemoresistance by upregulating EPHA2 through competitively sponging miR-372-3p.
Competitively sponging
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WebFeb 4, 2024 · In bladder cancer, MEG3 was found to function as a ceRNA for PTEN by competitively binding miR-494, thus repressing the proliferation, ... (PHLPP2) by sponging miR-27a. PHLPP2 could directly interact with and suppress the phosphorylation of c-JUN, thus downregulating the transcription of c-MYC and ultimately restraining tumour … WebJan 1, 2024 · circRNA_001275 upregulates Wnt7a expression by competitively sponging miR-370-3p to promote cisplatin resistance in esophageal cancer. Fangwen Zou, Shi ... that circRNA_001275 was upregulated in cisplatin-resistant esophageal cancer and promoted cisPlatin resistance by sponging miR-370-3p to upregulate Wnt7a expression. Expand. …
WebWhat does competitively mean? Meaning of competitively. competitively synonyms, pronunciation, spelling and more from Free Dictionary. Search Result for … WebDec 12, 2024 · LncRNA 3632454L22RiK can promote corneal epithelial wound healing in diabetic mice by sponging miR-181a-5p. The regulatory role of lncRNA MIAT in diabetic cardiomyopathy ... LncRNA H19 acts as a sponge for miR-29b and competitively represses miR-29b expression; therefore, it upregulates fibrillin 1 (FBN1), activates the transforming ...
WebApr 2, 2024 · LNIC00612 modulated the expression of E-cadherin and vimentin by competitively sponging miR-590 to elevate the expression of PHF14, thus affecting BC cellular epithelial-mesenchymal transition (EMT). Our results indicate that LINC00612 enhances the proliferation and invasion ability of BC cells by sponging miR-590 to … WebDec 1, 2024 · RMRP-mediated an increased level of IGF2 expression promotes CRC progression and metastasis by competitively sponging IGF2R. mPEG-DSPE liposomes encapsulated with siRNA HIF1α-AS2 significantly prevents the progression of CRC, indicating that HIF1α-AS2 might be a potential biomarker and therapeutic target for CRC …
WebDec 30, 2024 · This study using western blot assay validated that circNFIX could promote RPN2 expression by competitively sponging miR-378e, uncovering the ceRNA network of circNFIX/miR-378e/RPN2 in glioma. Xenograft model is responsible for the preclinical trials in glioma pathogenesis . Furthermore, we used T98 and U251 xenograft model to …
WebMar 10, 2024 · CircVPS13C functions as a key regulator of pituitary adenoma growth by competitively interacting with a ribosome-binding protein of the endoplasmic reticulum ... and invasion by sponging miR-153-3p, then determining Snail upregulation . In cervical cancer, circRNA-000284 induces tumor cell proliferation and invasion by sponging miR … meerconcepte ug norderneyWebFeb 24, 2024 · For example, circ-ITCH suppresses glycolysis of ovarian cancer cells by competitively sponging miR-106a to enhance the expression of E-cadherin (CDH1) . In addition, a study revealed that circ-ITCH downregulated the expression of glucose transporter type 1 (GLUT1) and suppressed glucose uptake to inhibit melanoma cell … name j is not defined翻译meer decision regarding storage tanks and psmLINC00668 regulated SOCS5 expression through competitively sponging miR-518c-3p to promote cell proliferation in glioma. a–b qRT-PCR and western blot respectively examined the mRNA and protein levels of SOCS5 in sh-LINC00668#1 group, sh-LINC00668#1 + miR-518c-3p-inhibitor or sh-NC group. See more In this study, 36 pairs of glioblastoma tissues and normal tissues were collected from recruited patients with glioblastoma at Shanxi Dayi Hospital from 2013 to 2024. Tissues were snap frozen in liquid nitrogen at once and … See more Total RNA was extracted using Trizol reagent (Invitrogen) and subjected to reverse-transcription using the TransScript First-Strand cDNA … See more Normal human astrocytes (NHAs) and human glioblastoma cells (T98G, U87, U251 and A172) were purchased from American Type Culture Collection (ATCC; Manassas, VA, … See more Specific shRNAs against LINC00668 (sh-LINC00668#1/#2) and corresponding NC (sh-NC), together with the pcDNA3.1 vector targeting … See more meercroft tasmaniaWebMay 30, 2024 · In the ceRNA network of CRC, H19 up-regulates various cancer-related mRNA by competitively sponging various miRNA, and participates in PI3K–Akt signaling pathway in this manner. Cox regression and correlation analysis showed that H19 and some other competing endogenous RNAs in the network are associated with poor prognosis … meerchaert mark m. : mathematical modellingWebMar 24, 2024 · Mechanistically, lncRNA LBX2-AS1 could elevate the expression of BRD4, an oncogene, by competitively binding to miR-597-3p. More importantly, knockdown of lncRNA LBX2-AS1 increased the sensitivity of OS cells to the BRD4 inhibitor JQ-1. Finally, the tumor growth of OS cell xenografts was constrained in vivo in the presence of … name job titles for top managersWebDec 4, 2024 · In the mouse stroke model obtained by transient middle cerebral artery occlusion, circDLGAP4 functioned as an endogenous miR-143 sponge to increase the expression of the miR-143 target HECTD1, thus decreasing infarct area and BBB damage. 40 Similarly, circHECW2 upregulates ATG5 expression by competitively sponging miR … meercut mowing