Cisplatin s1166
WebJan 24, 2024 · Cisplatin induces dysregulation of GSH metabolism in the renal tubules. (A) The enriched signaling pathways in cisplatin-induced kidneys using KEGG analysis, … WebFeb 21, 2024 · The resistant cell line DLD1 was established in vitro by intermittent exposure to different concentrations of cisplatin (S1166, selleck) in stepwise increments of time. …
Cisplatin s1166
Did you know?
WebSep 9, 2024 · BRCA1 maintains genome integrity and suppresses tumorigenesis by promoting homologous recombination (HR)-mediated repair of DNA double strand breaks (DSB) and DNA damage-induced cell cycle checkpoints. Phosphorylation of BRCA1 by ATM, ATR, CHK2, CDK, and PLK1 kinases has been reported to regulate its functions. WebMay 9, 2024 · Glutathione peroxidase 4 (GPX4) is a key regulator of ferroptosis where it utilizes reduced glutathione to convert lipid hydroperoxides to lipid alcohols, which mitigate lipid peroxidation and...
WebSep 18, 2024 · NCBI Bookshelf WebCisplatin (NSC 119875, Cisplatinum, cis-diamminedichloroplatinum II, CDDP, cis DDP, DDP) is an inorganic platinum complex, which is able to …
WebALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome Application of stem cell biology to breast cancer research has been limited by the lack of simple methods for identification and isolation of … WebApr 1, 2024 · Cell cultures were continued for 48 h after treatment with the indicated cisplatin doses or irradiation. For drug treatment, the cells were cultured 48 h after treatment with indicated cisplatin (S1166, selleckchem) doses. The radiation was done by using Faxitron Multirad 350. Western blot
WebJan 2, 2024 · First-line treatment with cisplatin-based combination chemotherapy affords an objective response rate (ORR) ranging from 46% to 64% and a progression-free survival (PFS) of 7.7 to 9.5 months ( 2–5 ).
WebJul 16, 2024 · Cisplatin or DMSO pre-treated cells were centrifuged and resuspended in a serum-free medium. Then 200 μl cell suspension (containing 2 × 10 4 cells) were added … software systems technical designsWebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 … slow motion draw swingWebOct 28, 2024 · As shown, cisplatin treatment induced dilated tubules with hyaline casts and cell detachment, which was blocked by co-treatment with ectopic ANXA2 (Fig. 2J ). Consistently, TUNEL staining also... slow motion drama gamesWebJun 17, 2024 · Cisplatin is an effective chemotherapeutic drug used for various solid tumors; however, AKI associated with cisplatin treatment limits its clinical usage [ 3 ]. High concentration of... software t300WebCisplatin (S1166, Selleck) was administered via intraperitoneal (i.p.) injection at a sin- gle dose of 18 mg/kg. Lansoprazole (L8533, Sigma) was administered via i.p. injection at a … software system testing and quality assuranceWebMar 20, 2024 · Cisplatin (CDDP) is a platinum-based antitumor drug [ 1 ]. Its widespread use in the treatment of breast cancer, ovarian cancer, and other cancers has greatly improved the survival rate of patients [ 1 – 4 ]. However, this process is often accompanied by serious side effects, including nephrotoxicity and ototoxicity [ 5 ]. slow motion drama definitionWebCisplatin is an antineoplastic drug used for the treatment of cancer patients with a variety of different malignancies. Application Cisplatin may be used as an analytical reference … slow motion drama